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Welcome to Bluxome Center

A neighborhood space for community and educational events in central SOMA





A Brief History of the “SoMa” Community

San Francisco’s most rapidly changing neighborhood, SoMa, or South of Market, continues to see its older residential neighborhoods revitalized and its former industrial areas redeveloped into towering condos, new convention centers, and office parks. Now, known to us as the vibrant, diverse microcosm of sub-neighborhoods we love today, SoMa’s current landscape belies its once much flatter, more confined origins.

In 1847, South of Market was officially referred to by an arguably equally pedestrian name, the “100 Vara Business District”—100 vara being a surveying unit of measure that is equivalent to about a city block. The new subdivision that expanded south of Market Street was a flourishing pioneer community that largely consisted of low-density residential buildings and an emerging industrial area with flourishing neighborhood businesses. By the early 20th century, the block and the surrounding region saw an influx of European immigrants who contributed to its heavy industrial scene, complete with a vast network of cable cars that carried the booming city’s residents and occupants along the long blocks of Mission, Folsom, Bryant Streets, and so on.

Eventually, the area south of Market Street became known as “South of the Slot” in reference to the street channels housing the cables along which its iconic cable cars traveled. It is still affectionately referred to as such by some long-standing members of the community.

More commonly today, this larger district, which encompasses a variety of sub-neighborhoods, restaurants, large companies, and civic centers, is referred to as “South of Market,” while others prefer the diminutive “SoMa” — as a nod to SoHo (South of Houston Street) of New York City, which in turn is a tip of the hat to the original Soho area of London.

Today, no longer does SoMa employ cable cars. And many of the low-density residential buildings have since grown considerably taller. But by whatever name you call it—SoMa, 100 Vara, or the Slot—South of Market continues to be a hub for development and growth and is home to a thriving and diverse community.

About Alexandria

Alexandria is about more than real estate. Through our dynamic and collaborative life science and technology campuses, impactful corporate responsibility initiatives, meaningful thought leadership programs, and sophisticated investment capital, we are building the future of life-changing innovation. Click here to learn more about our company.



Founded in 1994, we pioneered the life science real estate niche. More than 20 years later, Alexandria is the leader in owning, operating, and developing collaborative life science and technology campuses that support some of the world’s most innovative companies in their pursuit of life-changing therapies and technologies for the benefit of humankind.
About Alexandria Real Estate


Alexandria Venture Investments is the strategic venture capital arm of Alexandria Real Estate Equities, Inc. Focusing on novel, breakthrough discoveries in biopharmaceuticals, diagnostics, research tools, agtech, and technology, we invest strategic capital in the most promising life science companies to foster the next generation of breakthrough discoveries and cutting-edge technologies.
About Alexandria's Thought Leadership


We convene our preeminent network and curate interactive programming, including the renowned Alexandria Summit®, to further enable innovation in life science and improve the lives of patients around the world. To date, we have made groundbreaking advances as a result of the Alexandria Summits focused around some of the most important healthcare topics, including oncology, neuroscience, medical research philanthropy, digital health, infectious diseases, healthcare economics, and agriculture innovation.
Alexandria's Corporate Responsibility


As part of our commitment to making a positive impact, we focus on sustainability, philanthropy, and volunteer programs to enrich the communities in which we live and work. We put sustainability into action by creating environmentally responsible, highly dynamic urban campuses designed to promote health and wellness, and we dedicate our company resources, people, network, and expertise to provide support to non-profit organizations doing critical work in medical research, STEM education, military support services, and local communities.


61 Bluxome Street San Francisco, California


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61 Bluxome Street
San Francisco, California


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*photos courtesy of The Mowgli

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